Traits of Prions and Their Effects on Human Beings

 Traits of Prions and the Effects in Human Beings Article

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Traits of Prions and

Their Effects on Humans

Dennis Wei

Saint Paul High School

CHARACTERISTICS OF PRIONS AND THEIR RESULTS 2 MATERIAL

Abstract3

Discovery4

What's a Prion5

Just how Prions Replicate6

How Prions kill6

A directory of Prion Diseases7

Human Prion Diseases7

Creature Prion Diseases7

About BSE8

Human Prion Diseases in the United States8

What is the procedure for prion diseases? on the lookout for

The Fatalness of Prions9

The importance of prion research9

References11

ATTRIBUTES OF PRIONS AND THEIR RESULTS 3 Summary

This daily news explores distinct definitions of prion. Prion is a kind of necessary protein; it doesn't include any GENETICS or RNA. It's different from virus but both of prion and disease can bring to human beings illnesses. It's so hard to explanation prion, mainly because whether prion is a beast is still a debatable question. This kind of paper shows some characteristics of prion and the dissimilarities between regular proteins and prions plus some prion illnesses that have solid effects on human beings. In addition, it shows the history of the discovery of prion in the twentieth century. Keywords: protein, prion, disease

QUALITIES OF PRIONS AND THEIR RESULTS 4 Attributes of Prions and

Their Effects in Human Beings

Prions are aminoacids that are exceptional in their ability to reproduce by themselves and become infectious (Learn. Geneticsв„ў, 2012). Prion diseases affect the nervous program in humans and animals. In people, prion diseases generally caused memory space changes, persona changes, a decline in intellectual function (dementia). There is no way to find in the event that people have prion diseases, and these illnesses lead to death within a several months to several years. Discovery

In the 1950s, there was a form of disease present in the highlands of New Guinea. Most people within a tribe had been infected during those times, and most people of that tribe died from your disease that was called " kuru” simply by them (Learn. Genetics™, 2012). Most people thought that this disease was caused by a kind of malware which people didn't find out yet. Today we know that the illness is not caused by " kuru”, the actual pathogen is a type of protein referred to as prion. Prions cannot be killed by radioactive rays which could destroy nucleic acid just like DNA and RNA. That was a significant reason why man of science realized that prion was not a type of virus. Almost 50 years ago, an English biologist had an audacious hypothesis: there is a kind of " virus” that didn't include DNA or perhaps RNA. Yet he don't have enough data to hold his hypothesis, so that he could hardly testify his found. Simply by 1996, bovine spongiform enceohalopathy (BSE) killed 16, 000 cattle in the uk, and then, doze English teens died from new variant Creutzfeldt-Jakob disease (vCJD). The TRAITS OF PRIONS AND THE EFFECTS your five news built British incredibly nervous, no-one wanted to take in beef at that time. The eruption of BSE attracted plenty of scientists around the globe. The research to prion started to be a very important function at that time. Doctor Stanley Prusiner did a whole lot of research that about this kind of " virus” then coined the term " prion" (proteinaceous infectious particle). This individual went on to win the Nobel Award in Medication in 97. What's a Prion

Prions are aminoacids that are exceptional in their capability to reproduce on their own and become contagious. They can occur in two varieties called PrP-sen (or PrPc) and PrP-res (or PrPsc). All attributes of these two forms are same except the shapes.

PrP-sen (or PrPc) implies that this kind of prions is sensitive and these kinds of prions are typical. They are produced by normal healthy and balanced cells. Almost all of PrP-sen exist mainly in neurons in the brain, yet sometimes they are also found in additional cell types. Scientists don't know the exact function of PrP-sen, but they located some evidence that could...

References: CDC -- Bovine Spongiform Encephalopathy (BSE). (n. deb. ). Centers for Disease Control and Prevention. Recovered May 9, 2013, by http://www.cdc.gov/ncidod/dvrd/bse/

CDC - Prion Diseases. (2010, January 1). Centers for Disease Control and Reduction. Retrieved Might 9, 2013, from http://www.cdc.gov/ncidod/dvrd/prions/

Prion disease. (n. deb. ). Inherited genes Home Reference. Retrieved May possibly 9, 2013, from http://ghr.nlm.nih.gov/condition/prion-disease

Prions: Within the Trail of Killer Aminoacids. (n. d. ). Study. Geneticsâ„¢. Gathered May on the lookout for, 2013, coming from http://learn.genetics.utah.edu/content/begin/dna/prions/

Prusiner, S. (n. d. ). The Prion Diseases. (1995, January) Clinical American. Retrieved May on the lookout for, 2013, coming from mvc. bioweb. dcccd. edu/weblinks/scbsesp. htm

Robert C. Holman, Ermias D. Belay, Krista Y. Christensen, Ryan A. Maddox, Arialdi M. Delicado, Arianne Meters. Folkema, Credit L. Haberling, Teresa A. Hammett, Kenneth D. Kochanek, James L. Sejvar, Lawrence B. Schonberger. (2010, January 1). Human Prion Conditions in the United States. PLOS ONE: increasing the publication of peer-reviewed science. Retrieved May 11, 2013, by http://www.plosone.org/article/info:doi/10.1371/journal.pone.0008521